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Ensemble mean of the effective survey response operator (left panel) and corresponding standard deviation map (right panel). The ensemble mean is renormalized by the highest pixel value, as the absolute value does not have a meaning independent of the mean density and the radial selection function. The two above maps should be compared to the north galactic cap of the map in the lower right panel of Fig. 2. The ensemble mean is quite different owing to the introduced star contamination, which could introduce contamination in targets. This manifests itself by an over-completeness on the edge of the map. The right map shows a similar trend, but touching the uncertainty on the selection this time.
|Open with DEXTER|
|In the text|
|nbsp;||Fale Conosco nbsp; nbsp;|
|Modifying factor: Not applicable.|
|Animal to human dosimetric adjustment: Not applied. As noted, the cardiac sensitization model with the dog heart is considered a good model for humans.|
|Time scaling: Not applied. Cardiac sensitization is an exposure and blood concentration related threshold effect. Several studies have shown that blood concentrations of halocarbons do not increase greatly with time after 15 #x02013;55 min of exposure, and exposure duration did not influence the concentration at which the effect occurred.|
|Data adequacy: The study was well conducted and documented. Supporting data include both human and animal studies. Animal studies covered acute, subchronic, and chronic exposure durations and addressed systemic toxicity as well as neurotoxicity, reproductive and developmental effects, cardiac sensitization, genotoxicity, and carcinogenicity. Other effects in animal studies occurred at much higher concentrations or with repeated exposures; the latter are not relevant for setting short-term exposures. No deaths occurred in several species of animals exposed for various periods of time to concentrations less than those requiring supplemental oxygen (approximately 700,000 ppm).|
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