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The relationship of reduction in incidence of coronary heart disease to cholesterol lowering.
The maximum daily dose of Crestor is 40 mg.
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All subjects in whom study medication is discontinued will be followed for the duration of the trial and included in data analyses.
However, follow-up with respect to safety for the prespecified secondary end points (i.
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Effects of Rosuvastatin on Coronary Flow Reserve and Metabolic Mismatch in Patients With Heart Failure (from the CORONA Study).
The role of adipocyte XBP1 in metabolic regulation during lactation.
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Talk to your doctor about the risks of taking rosuvastatin.
Such solution may for example be prepared by starting with rosuvastatin sodium as a solid, and adding the solid to an alcohol.
Clinician's Guide to the ABCs of Cardiovascular Disease Prevention: The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease and American College of Cardiology Cardiosource Approach to the Million Hearts Initiative.
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Acceleration of re-endothelialization and inhibition of neointimal formation using hybrid biodegradable nanofibrous rosuvastatin-loaded stents.
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There were 155 deaths from cardiovascular causes in the group given 10 mg of atorvastatin (3.
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From the time of randomization through March 30, 2008, a total of 173 participants in the rosuvastatin group had either venous thromboembolism or a primary cardiovascular end point (32 had venous thromboembolism as the first event), and 305 participants in the placebo group had either venous thromboembolism or a primary cardiovascular event (56 had venous thromboembolism as the first event) ( Table 3 Occurrence of Venous Thromboembolism, Cardiovascular Disease, and Death According to Study Group.
Crestor has been approved by the FDA.
Statins have additional benefits beyond lowering cholesterol levels (pleiotropic effects); they also help the lining of the blood vessels work better (improved endothelial function), enhance the stability of atherosclerotic plaques, reduce the amount of inflammation and damage done to cells through oxidation (oxidative stress), and keep blood platelets from clumping together (platelet aggregation), thereby reducing the risk of a blood clot (thrombus).
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However, half of all myocardial infarctions and strokes occur among apparently healthy men and women with levels of low-density lipoprotein (LDL) cholesterol that are below currently recommended thresholds for treatment.
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Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin.
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Endothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298.
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Similarly, two transport or binding sites have been proposed for MRP2.
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The dosage may be increased if this target is not reached.
This public notice function will be subverted if the “error” requirement is read out of the reissue statute and patentees are given free reign to rewrite their claims whenever they find it expedient to do so.
Klaricid can cause the following side effects: muscle pain, joint pain, abdominal pain, liver damage (jaundice-yellowing of the skin and eyes, dark urine, loss of appetite), hearing loss, tinnitus, nausea, vomiting, diarrhea (can be followed with blood in the stool), allergies (signs of allergy include: rash, itching, redness, swelling, anaphylactic shock), increased sweating, dizziness, nervousness, headaches, mood changes, inflammation of the pancreas, change of tongue and teeth color and others.
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Effects of the dose of erythropoiesis stimulating agents on cardiovascular events, quality of life, and health-related costs in hemodialysis patients: the clinical evaluation of the dose of erythropoietins (C.
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Few cases of muscle and liver problems associated with the use of Crestor and other similar medicines have been reported.
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AURORA and 4D are not the only studies to show a lack of benefit of statin therapy in specific populations.
The PK properties of rosuvastatin are based on first-order kinetics in the dose range tested.
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Results from Protective effect of Rosuvastatin and Antiplatelet Therapy On contrast-induced acute kidney injury and myocardial damage in patients with Acute Coronary Syndrome (PRATO-ACS Study).
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Ensure you mention any of the following health and wellness troubles you have, as a few of them could influence the dose you are being recommended: underactive thyroid, a muscle condition, kidney condition, a recent record of a surgical procedure, serious infection, and seizure disorder.
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Follow-up visits were scheduled to occur at 13 weeks and then 6, 12, 18, 24, 30, 36, 42, 48, 54, and 60 months after randomization.
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In 2013 Crestor was the fourth-highest selling drug in the United States, accounting for approx.
What kinds of side effects may occur?
Cholesterol Goals: Moving from Numbers to Treatment.
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Statin Therapy in Patients With Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention (from the Evaluation of Drug Eluting Stents and Ischemic Events Registry).
The replication of HCV is largely dependent on the use of host cellular components, and lipid moieties or lipid-containing molecules, such as sterol proteins, may play an important role in facilitating viral replication, either via assembly, packaging, or release.
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It is worth mentioning that this rapidly evolving science could make many prescriptive aspects related to transporter-based DDI described in the draft US guidance outdated soon after it is finalized.
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In pulmonary edema the left ventricle fails to eject sufficient blood, and pressure increases in the lungs because of the accumulated blood.
All rosuvastatin doses tested were well tolerated.
Statins in patients with chronic kidney disease: why, who and when?
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Administration of antihypertensive drugs generally halts disease progression in white populations, but has little effect in slowing kidney disease among blacks, and additional treatment such as bicarbonate therapy is often required.
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The short answer is that of statins still on the market, the milligram for milligram cholesterol lowering potency of rosuvastatin exceeds all others, a fact exploited in advertising campaigns.
Heart rate management in coronary artery disease: the CLARIFY registry.
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