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I have suffered from RLS and PLMD for years. The last few years I've been taking Sinemet, which worked great in the beginning but gradually lost its effectiveness. I was up to 3 pills a day and the RLS was worse than ever. My neurologist just started me on Mirapex and it is incredible. One pill at night and I get a good nights sleep. I'm also not getting the RLS during the daytime anymore. I haven't felt this good in a long time! No side effects either.



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My granny was really bad last year when she had an outbreak of Parkinson disease. We took her to the family doctor and he advised us to try Mirapex. The medication is a miracle. Granny has no mo shakiness and she can move ok, not as fast as younger people but her movements are not that slow and painful as they used to be last year.

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On the basis various disease type the global restless legs syndrome market can be broadly bifurcated as etiology and pathogenesis, iron deficiency, genetic factors, neurological disturbances and others.

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RLS is often related to folate deficiency, particularly the form of RLS that is associated with familial inheritance and with pregnancy.

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RLS usually does not indicate the onset of other neurological disease.

A lot of people erroneously believe that generic medications need more time to work, this is not true.

Physical side effects are usually tolerable, or may be managed using over-the-counter medicines or changes in lifestyle.

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Since the 1950s, it has been known that iron therapy, even without the presence of anemia has benefits for RLS symptoms.

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Generic drugs contain the same active ingredients as the original brand drugs.

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The safety and effectiveness of generic drugs are established by the fact that all of them go through the FDA review and approval procedure.

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease.

It works by acting in place of dopamine, a natural substance in the brain that is needed to control movement.

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The first affected arm may not swing fully when walking, and the foot on the same side may scrape the floor.

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Los pacientes deben ser alertados sobre los efectos sedantes potenciales de pramipexol incluyendo la somnolencia y la posibilidad de quedarse dormido durante las actividades propias de la vida diaria.

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Throughout the trial, patients treated with pramipexole dihydrochloride tablets had a mean of 4 "off" hours per day, while placebo-treated patients continued to experience 6 "off" hours per day.

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The use of this class of drug earlier in the treatment cycle represents current theory, suggesting that many of the late treatment complications associated with PD treatment are a result of the short half-life of levodopa.

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In effect, it acts like a substitute for dopamine.

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Talk to your doctor about your specific risk and what skin symptoms to watch for.

Common side effects include agitation, insomnia, nausea, anorexia, and orthostatic hypotension.

It also may help patients with RLS who are undergoing hemodialysis.

In addition to the adverse events reported during clinical trials, the following adverse reactions have been identified during post-approval use of pramipexole dihydrochloride tablets, primarily in Parkinson's disease patients.

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Dystonia in Parkinson disease commonly consists of a foot involuntary turning in (inversion) or down (plantar flexion), often associated with cramping or aching in the leg.

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